ABSTRACT A physiologically based pharmacokinetic model for di-(2-ethylhexyl) terephthalate (DEHTP) based on a refined model for di-(2-propylheptyl) phthalate (DPHP) was developed to interpret the m...
Read moreABSTRACT A physiologically based pharmacokinetic model for Di-(2-propylheptyl) phthalate (DPHP) was developed to interpret the biokinetics in humans after single oral doses. The model was parameter...
Read moreABSTRACT This study investigates possible effects of in utero exposure of rats to a low dose (125 mg/kg bw/day) and a high dose (750 mg/kg bw/day) of Diisononyl phthalate (DINP) during the masculin...
Read moreABSTRACT A physiologically based pharmacokinetic (PBPK) model for di-isononyl phthalate (DiNP) was developed by adapting the existing models for di(2-ethylhexyl) phthalate (DEHP) and di-but...
Read moreDiscover the main used plasticisers and their applications in Ullmann's Encyclopedia of industrial chemistry. Read more about the contribution of European Plasticisers to the Encyclopedia h...
Read moreDevelopment, Testing, Parameterization, and Calibration of a Human Physiologically Based Pharmacokinetic Model for the Plasticizer, Hexamoll® Diisononyl-Cyclohexane-1, 2-Dicarboxylate Using In Silico...
Read moreLearn more about the methodology developed by Professors W. Dekant and J.Bridges to make scientific evaluations more consistent when testing a hypothesis, using predefined criteria. Our factsheet allo...
Read moreABSTRACT Hazard assessment of chemicals usually applies narrative assessments with a number of weaknesses. Therefore, application of weight of evidence (WoE) approaches are often mandated but gui...
Read moreABSTRACT Quantitative weight of evidence (QWoE) methodology utilizes detailed scoring sheets to assess the quality/reliability of each publication on toxicity of a chemical and gives numerical scores...
Read moreIntroduction Phthalates are used in cosmetics, flooring adhesives, medical tubings, toys, food packaging materials, and so forth. A number of reviews of the epidemiology of phthalates have been publi...
Read moreINTRODUCTION European Plasticisers (formerly European Council for Plasticisers and Intermediates - ECPI) commissioned PE International to conduct an LCA study with the goal to setup a PlasticsEurope...
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